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A new method of studying collapsibility of loess

Yuanqing ZHU , Zhenghan CHEN ,

《结构与土木工程前沿（英文）》 2009年 第3卷 第3期   页码 305-311 doi: 10.1007/s11709-009-0040-3

摘要： A new triaxial testing system that could control suction in wetting-induced collapsible tests was successfully developed to study the suction effects on wetting-induced collapsible deformation. The pedestal of the triaxial cell was made up of two parts, and the equipment not only could control suction but also could make water accessible to soil. A pressure/volume-controlled equipment was combined with the triaxial system to measure the water volume absorbed by samples accurately and to add pressure on water to filtrate into the sample. The apparatus could measure volume change precisely and keep the deviator stress unvaried, as well as measure the volume of water filtrating into the samples exactly. A triaxial collapsible testing procedure was described using the new apparatus for undisturbed collapsible loess with controlled suction. Furthermore, a series of double triaxial collapsible tests were conducted under different suctions and the same net cell pressure, and tests under different net cell pressures and the same suction were also done. It was indicated that the collapsible deformation increased with the increasing suction, and the effect of the net cell pressure on collapsible deformation was remarkable. The new triaxial apparatus was a useful facility to study the collapsible behavior of loess.

关键词： triaxial apparatus for collapsible soils     controlled suction     pressure/volume controlled equipment     double triaxial collapsible test     single triaxial collapsible test    

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Prediction of hydro-suction dredging depth using data-driven methods

《结构与土木工程前沿（英文）》 2021年 第15卷 第3期   页码 652-664 doi: 10.1007/s11709-021-0719-7

摘要： In this study, data-driven methods (DDMs) including different kinds of group method of data handling (GMDH) hybrid models with particle swarm optimization (PSO) and Henry gas solubility optimization (HGSO) methods, and simple equations methods were applied to simulate the maximum hydro-suction dredging depth (hs). Sixty-seven experiments were conducted under different hydraulic conditions to measure the hs. Also, 33 data samples from three previous studies were used. The model input variables consisted of pipeline diameter (d), the distance between the pipe inlet and sediment level (Z), the velocity of flow passing through the pipeline (u0), the water head (H), and the medium size of particles (D50). Data-driven simulation results indicated that the HGSO algorithm accurately trains the GMDH methods better than the PSO algorithm, whereas the PSO algorithm trained simple simulation equations more precisely. Among all used DDMs, the integrative GMDH-HGSO algorithm provided the highest accuracy (RMSE = 7.086 mm). The results also showed that the integrative GMDHs enhance the accuracy of polynomial GMDHs by ~14.65% (based on the RMSE).

关键词： sedimentation     water resources     dam engineering     machine learning     heuristic    

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Magnetohydrodynamic slip flow and diffusion of a reactive solute past a permeable flat plate with suction

Krishnendu BHATTACHARYYA, G. C. LAYEK

《化学科学与工程前沿（英文）》 2011年 第5卷 第4期   页码 471-476 doi: 10.1007/s11705-011-1130-z

摘要： The magnetohydrodynamic (MHD) boundary layer slip flow and solute transfer over a porous plate in the presence of a chemical reaction are investigated. The governing equations were transformed into self-similar ordinary differential equations by adopting the similarity transformation technique. Then the numerical solutions are obtained by a shooting technique using the fourth order Runge-Kutta method. The study reveals that due to the increase in the boundary slip, the concentration decreases and the velocity increases. On the other hand, with an increase in the magnetic field and mass suction, both boundary layer thicknesses decreased. As the Schmidt number and the reaction rate parameter increases, the concentration decreases and the mass transfer increases.

关键词： slip flow     MHD boundary layer     reactive solute diffusion     flat plate     suction/injection    

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heat source/sink on unsteady MHD boundary layer flow and heat transfer over a shrinking sheet with suction

Krishnendu Bhattacharyya

《化学科学与工程前沿（英文）》 2011年 第5卷 第3期   页码 376-384 doi: 10.1007/s11705-011-1121-0

摘要： In this paper, an investigation is made to study the effects of radiation and heat source/sink on the unsteady boundary layer flow and heat transfer past a shrinking sheet with suction/injection. The flow is permeated by an externally applied magnetic field normal to the plane of flow. The self-similar equations corresponding to the velocity and temperature fields are obtained, and then solved numerically by finite difference method using quasilinearization technique. The study reveals that the momentum boundary layer thickness increases with increasing unsteadiness and decreases with magnetic field. The thermal boundary layer thickness decreases with Prandtl number, radiation parameter and heat sink parameter, but it increases with heat source parameter. Moreover, increasing unsteadiness, magnetic field strength, radiation and heat sink strength boost the heat transfer.

关键词： MHD boundary layer     unsteady flow     heat transfer     thermal radiation     heat source/sink     shrinking sheet     suction/injection    

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Synthesis and characterization of biocompatible polyurethanes for controlled release of hydrophobic and

Juichen YANG,Hong CHEN,Yuan YUAN,Debanjan SARKAR,Jie ZHENG

《化学科学与工程前沿（英文）》 2014年 第8卷 第4期   页码 498-510 doi: 10.1007/s11705-014-1451-9

摘要： Design of biocompatible and biodegradable polymer systems for sustained and controlled release of bioactive agents is critical for numerous biomedical applications. Here, we designed, synthesized, and characterized four polyurethane carrier systems for controlled release of model drugs. These polyurethanes are biocompatible and biodegradable because they consist of biocompatible poly(ethylene glycol) or poly(caprolactone diol) as soft segment, linear aliphatic hexamethylene diisocyanate or symmetrical aliphatic cyclic dicyclohexylmethane-4,4′-diisocyanate as hard segment, and biodegradable urethane linkage. They were characterized with Fourier transform infrared spectroscopy, atomic force microscope, and differential scanning calorimetry, whereas their degradation behaviors were investigated in both phosphate buffered saline and enzymatic solutions. By tuning polyurethane segments, different release profiles of hydrophobic and hydrophilic drugs were obtained in the absence and presence of enzymes. Such difference in release profiles was attributed to a complex interplay among structure, hydrophobicity, and degradability of polyurethanes, the size and hydrophobicity of drugs, and drug-polymer interactions. Different drug-polyurethane combinations modulated the distribution and location of the drugs in polymer matrix, thus inducing different drug release mechanisms. Our results highlight an important role of segmental structure of the polyurethane as an engineering tool to control drug release.

关键词： phase structure     degradation     polyurethanes     controlled release     drug delivery    

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On the MHD squeeze flow between two parallel disks with suction or injection via HAM and HPM

null

《机械工程前沿（英文）》 2014年 第9卷 第3期   页码 270-280 doi: 10.1007/s11465-014-0303-0

摘要：

An analysis has been performed to study the problem of magneto-hydrodynamic (MHD) squeeze flow of an electrically conducting fluid between two infinite, parallel disks. The analytical methods called Homotopy Analysis Method (HAM) and Homotopy Perturbation Method (HPM) have been used to solve nonlinear differential equations. It has been attempted to show the capabilities and wide-range applications of the proposed methods in comparison with a type of numerical analysis as Boundary Value Problem (BVP) in solving this problem. Also, the velocity fields have been computed and shown graphically for various values of physical parameters. The objective of the present work is to investigate the effect of squeeze Reynolds number, Hartmann number and the suction/injection parameter on the velocity field. Furthermore, the results reveal that HAM and HPM are very effective and convenient.

关键词： Homotopy Analysis Method     Homotopy Perturbation Method     incompressible flow     magneto-hydrodynamic flow     parallel disks    

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Studying the stress-suction coupling in soils using an oedometer equipped with a high capacity tensiometer

Trung Tinh LE, Yu-Jun CUI, Juan Jorge MU?OZ, Pierre DELAGE, Anh Minh TANG, Xiang-Ling LI

《结构与土木工程前沿（英文）》 2011年 第5卷 第2期   页码 160-170 doi: 10.1007/s11709-011-0106-x

摘要： In the context of research into deep nuclear waste disposal, various works have concerned the hydromechanical behavior of Boom clay, a stiff plastic clay extracted in the SCK-CEN Underground Research Laboratory near the Mol City (Belgium), at a depth of 223 m. Due to some amount of smectite minerals in the clay fraction, Boom clay exhibits swelling properties when hydrated under low stresses. To investigate some aspects of the hydromechanical behavior of Boom clay, oedometer compression tests were carried out on samples of Boom clay close to saturation and submitted to an initial suction. During oedometer compression, the changes in suction with increased vertical stress are monitored by means of a high capacity tensiometer installed at the bottom of the sample. Some aspects related to hydromechanical couplings are examined through the investigation of the changes in suction during oedometer compression, a somewhat delicate and poorly documented experimental approach. A comparison is also made with a completely different soil sample under suction, i.e. a statically compacted unsaturated low plasticity silt. Some technical difficulties typical of this new experimental approach are first described in detail so as to optimize the interpretation of the data obtained. The experiment allows the determination of the point at which suction is changed to positive pressure during compression. Below this point, the ratio between the vertical stress and the change in suction are determined. Above this point, the data show that positive pore pressures are dissipated in a common way. The suction/stress behavior during unloading is also described and discussed. Finally, an interpretation in terms of microstructure effects is provided for both samples. The experimental approach initiated here seems to provide interesting further application to better understand hydromechanical couplings in natural soils in relation with suction increase during stress release.

关键词： Oedometer     tensiometer     swelling     physicochemical and mechanical effects     stress/suction coupling     soil plasticity    

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Size-controlled green synthesis of silver nanoparticles assisted by L-cysteine

Wenchao Zhang,Lin Zhang,Yan Sun

《化学科学与工程前沿（英文）》 2015年 第9卷 第4期   页码 494-500 doi: 10.1007/s11705-015-1527-1

摘要： A green and size-controlled synthesis of silver nanoparticles (Ag NPs) in aqueous solution with the assistance of L-cysteine is presented. The size of Ag NPs decreases with the increase of L-cysteine concentration, and thus can be controlled by adjusting L-cysteine concentration. TEM analysis shows that Ag NPs with an average size of 3 nm can be produced in the presence of 1.0 mmol/L L-cysteine, about one sixth of the size of Ag NPs obtained in the absence of L-cysteine (17 nm). The as-synthesized silver colloidal solution is stable and can be stored at room temperature for at least two months without any precipitation. This L-cysteine assisted method is simple, feasible and efficient, and would facilitate the production and application of Ag NPs.

关键词： nanoparticles     silver     L-cysteine     size distribution     synthesis    

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Analysis and stabilization control of a voltage source controlled wind farm under weak grid conditions

《能源前沿（英文）》 2022年 第16卷 第6期   页码 943-955 doi: 10.1007/s11708-021-0793-5

摘要： This paper investigates and discusses the interaction stability issues of a wind farm with weak grid connections, where the wind turbines (WTs) are controlled by a new type of converter control strategy referred to as the voltage source (VS) control. The primary intention of the VS control method is to achieve the high-quality inertial response capability of a single WT. However, when it is applied to multiple WTs within a wind farm, its weak-grid performance regarding the stability remains concealed and needs to be clarified. To this end, a frequency domain model of the wind farm under the VS control is first developed. Based on this model and the application of a stability margin quantification index, not only the interactions between the wind farm and the weak grid but also those among WTs will be systematically assessed in this paper. A crucial finding is that the inertial response of VS control has negative impacts on the stability margin of the system, and the dominant instability mode is more related to the interactions among the WTs rather than the typical grid-wind farm interaction. Based on this knowledge, a stabilization control strategy is then proposed, aiming for stability improvements of VS control while fulfilling the demand of inertial responses. Finally, all the results are verified by time-domain simulations in power systems computer aided design/electromagnetic transients including DC(PSCAD/EMTDC).

关键词： weak grids     voltage source (VS) control     wind turbine (WT)     stabilization control     wind farm     inertial response    

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Chinese medicine patterns on patients with pneumoconiosis: a pilot double-blind, randomized, and placebo-controlled

《医学前沿（英文）》 2022年 第16卷 第5期   页码 736-744 doi: 10.1007/s11684-021-0870-5

摘要： Effective therapy options for pneumoconiosis are lacking. Traditional Chinese medicine (TCM) presents a favorable prospect in the treatment of pneumoconiosis. A pilot study on TCM syndrome differentiation can evaluate the clinical efficacy and safety of TCM and lay a foundation for further clinical research. A double-blind, randomized, and placebo-controlled trial was conducted for 24 weeks, in which 96 patients with pneumoconiosis were randomly divided into the control and treatment groups. Symptomatic treatment was conducted for the two groups. The treatment group was treated with TCM syndrome differentiation, and the control group was treated with placebo. The primary outcomes were the six-minute walking distance (6MWD) and the St. George Respiratory Questionnaire (SGRQ) score. The secondary outcomes were the modified British Medical Research Council Dyspnea Scale (mMRC), Chronic Obstructive Pulmonary Disease Assessment Test (CAT), Hospital Anxiety and Depression Scale (HADS), and pulmonary function. Only 83 patients from the 96 patients with pneumoconiosis finished the study. For the primary outcome, compared with the control groups, the treatment group showed a significantly increased 6MWD (407.90 m vs. 499.51 m; 95% confidence interval (CI) 47.25 to 135.97; P <0.001) and improved SGRQ total score (44.48 vs. 25.67; 95% CI −27.87 to −9.74; P <0.001). The treatment group also significantly improved compared with the control group on mMRC score (1.4 vs. 0.74; 95% CI −1.08 to −0.23; P =0.003), CAT score (18.40 vs. 14.65; 95% CI −7.07 to −0.43; P =0.027), and the total symptom score (7.90 vs. 5.14; 95% CI −4.40 to −1.12; P <0.001). No serious adverse events occurred. This study showed that TCM syndrome differentiation and treatment had a favorable impact on the exercise endurance and quality of life of patients with pneumoconiosis.

关键词： pneumoconiosis     randomized controlled trials     traditional Chinese medicine    

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Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

《能源前沿（英文）》 2022年 第16卷 第1期   页码 64-73 doi: 10.1007/s11708-021-0732-5

摘要： More flexibility is desirable with the proliferation of variable renewable resources for balancing supply and demand in power systems. Thermostatically controlled loads (TCLs) attract tremendous attentions because of their specific thermal inertia capability in demand response (DR) programs. To effectively manage numerous and distributed TCLs, intermediate coordinators, e.g., aggregators, as a bridge between end users and dispatch operators are required to model and control TCLs for serving the grid. Specifically, intermediate coordinators get the access to fundamental models and response modes of TCLs, make control strategies, and distribute control signals to TCLs according the requirements of dispatch operators. On the other hand, intermediate coordinators also provide dispatch models that characterize the external characteristics of TCLs to dispatch operators for scheduling different resources. In this paper, the bottom-up key technologies of TCLs in DR programs based on the current research have been reviewed and compared, including fundamental models, response modes, control strategies, dispatch models and dispatch strategies of TCLs, as well as challenges and opportunities in future work.

关键词： thermostatically controlled load     demand response     renewable energy     power system operation    

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All-in-one functional supramolecular nanoparticles based on pillar[5]arene for controlled generation,

《化学科学与工程前沿（英文）》 2023年 第17卷 第3期   页码 307-313 doi: 10.1007/s11705-022-2216-5

摘要： The storage and controlled release of singlet oxygen (1O2) have attracted increasing attention due to the wide application and microsecond lifetime of 1O2 in water. Herein we provide an integrated nanoplatform consisting of a diphenylanthracene derivative, a water-soluble pillar[5]arene and a photosensitizer tetrakis(4-hydroxyphenyl)porphyrin (TPP), that may provide the controlled generation, storage and release of singlet oxygen. We design a new diphenylanthracene derivative with two trimethylammonium bromide groups on both ends that can be well recognized by the pillar[5]arene. The formed nanocarriers can be used to load TPP through their supramolecular self-assembly. The resulting nanoparticles show good water-solubility and uniform spherical morphology. After laser irradiation (660 nm), the nanoparticles exhibit excellent ability for the generation and storage of 1O2. When the irradiated nanoparticles are heated above 80 °C, 1O2 can be released from the system. Therefore, in this paper we pioneer the use of noncovalent interaction to integrate the diphenylanthracene derivatives and photosensitizers into one functional system, which provides a new strategy for the controlled generation, storage and release of singlet oxygen. We believe this groundbreaking strategy will have a great potential in providing necessary amounts of 1O2 for the photodynamic therapy of tumors in dark.

关键词： storage and controlled release of singlet oxygen     supramolecular nanoparticles     noncovalent interactions     pillararenes     diphenylanthracene     photosensitizers    

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Stability analysis of layered slopes in unsaturated soils

Guangyu DAI; Fei ZHANG; Yuke WANG

《结构与土木工程前沿（英文）》 2022年 第16卷 第3期   页码 378-387 doi: 10.1007/s11709-022-0808-2

摘要： This study presents stability analyses of layered soil slopes in unsaturated conditions and uses a limit equilibrium method to determine the factor of safety involving suction stress of unsaturated soil. One-dimensional steady infiltration and evaporation conditions are considered in the stability analyses. An example of a two-layered slope in clay and silt is selected to verify the used method by comparing with the results of other methods. Parametric analyses are conducted to explore the influences of the matric suction on the stability of layered soil slopes. The obtained results show that larger suction stress provided in unsaturated clay dominates the stability of the layered slopes. Therefore, the location and thickness of the clay layer have significant influences on slope stability. As the water level decreases, the factor of safety reduces and then increases gradually in most cases. Infiltration/evaporation can obviously affect the stability of unsaturated layered slopes, but their influences depend on the soil property and thickness of the lower soil layer.

关键词： slope stability     suction stress     unsaturated soil     layered slope     limit equilibrium    

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Correction to: Highly degradable chitosan-montmorillonite (MMT) nanocomposite hydrogel for controlled

《环境科学与工程前沿（英文）》 2023年 第17卷 第8期 doi: 10.1007/s11783-023-1704-2

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Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

《化学科学与工程前沿（英文）》 2014年 第8卷 第2期   页码 225-232 doi: 10.1007/s11705-014-1429-7

摘要： Semi-solid materials represent an important category of inactive ingredients (excipients) of pharmaceutical products. Here we review several common semi-solid polymers currently used in the controlled release formulations of many drugs. These polymers are selected based on their importance and broad scope of application in FDA-approved drug products and include several polysaccharides (cellulose, starch, chitosan, alginate) and carbomers, a group of mucoadhesive synthetic polymers. Glyceride-based polymers used in self-emulsifying drug delivery systems (SEDDS) will also be discussed for its importance in formulating poorly water-soluble drugs. Unique features and advantages of each type of semi-solid materials are discussed and examples of their use in oral delivery of drugs are provided. Finally, future prospects of developing new and better semi-solid excipients are discussed with the objective of facilitating clinical translation.

关键词： controlled release     drug delivery     semi-solids     polymer     excipient    

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标题 作者 时间 类型 操作

A new method of studying collapsibility of loess

Yuanqing ZHU , Zhenghan CHEN ,

期刊论文

Prediction of hydro-suction dredging depth using data-driven methods

期刊论文

Magnetohydrodynamic slip flow and diffusion of a reactive solute past a permeable flat plate with suction

Krishnendu BHATTACHARYYA, G. C. LAYEK

期刊论文

heat source/sink on unsteady MHD boundary layer flow and heat transfer over a shrinking sheet with suction

Krishnendu Bhattacharyya

期刊论文

Synthesis and characterization of biocompatible polyurethanes for controlled release of hydrophobic and

Juichen YANG,Hong CHEN,Yuan YUAN,Debanjan SARKAR,Jie ZHENG

期刊论文

On the MHD squeeze flow between two parallel disks with suction or injection via HAM and HPM

null

期刊论文

Studying the stress-suction coupling in soils using an oedometer equipped with a high capacity tensiometer

Trung Tinh LE, Yu-Jun CUI, Juan Jorge MU?OZ, Pierre DELAGE, Anh Minh TANG, Xiang-Ling LI

期刊论文

Size-controlled green synthesis of silver nanoparticles assisted by L-cysteine

Wenchao Zhang,Lin Zhang,Yan Sun

期刊论文

Analysis and stabilization control of a voltage source controlled wind farm under weak grid conditions

期刊论文

Chinese medicine patterns on patients with pneumoconiosis: a pilot double-blind, randomized, and placebo-controlled

期刊论文

Applications of thermostatically controlled loads for demand response with the proliferation of variable

Meng SONG, Wei SUN

期刊论文

All-in-one functional supramolecular nanoparticles based on pillar[5]arene for controlled generation,

期刊论文

Stability analysis of layered slopes in unsaturated soils

Guangyu DAI; Fei ZHANG; Yuke WANG

期刊论文

Correction to: Highly degradable chitosan-montmorillonite (MMT) nanocomposite hydrogel for controlled

期刊论文

Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

期刊论文